Medical Use
Daybue is prescribed for the treatment of Rett syndrome in both adults and pediatric patients aged 2 years and older.
Recommended Dosage and Administration:
- -Dosage: Administer twice daily, in the morning and evening, based on the patient’s weight.
- -Administration: Can be taken with or without food.
Dosage by Patient Weight:
- -9 kg to less than 12 kg: 5,000 mg (25 mL) twice daily
- -12 kg to less than 20 kg: 6,000 mg (30 mL) twice daily
- -20 kg to less than 35 kg: 8,000 mg (40 mL) twice daily
- -35 kg to less than 50 kg: 10,000 mg (50 mL) twice daily
- -50 kg or more: 12,000 mg (60 mL) twice daily
Administration Options:
- -Can be taken orally or via a gastrostomy (G) tube.
- -For gastrojejunal (GJ) tube administration, doses must be given through the G-port.
Warning & Precautions
Diarrhea: Many patients may experience diarrhea while taking Daybue. Before starting Daybue, patients should stop using laxatives. If diarrhea occurs, they should begin antidiarrheal treatment, increase fluid intake, and inform their healthcare provider. If severe diarrhea or dehydration is suspected, consider interrupting, reducing the dose, or discontinuing Daybue.
Weight Loss: Some patients may experience weight loss. Regularly monitor weight and consider interrupting, reducing the dose, or discontinuing Daybue if significant weight loss is observed.
Adverse Reactions:
The most common adverse reactions (reported in at least 10% of patients treated with Daybue and at least 2% more frequently than in the placebo group) are diarrhea and vomiting.
Drug Interactions:
- -For orally administered CYP3A4-sensitive substrates, closely monitor for adverse reactions when used together.
- -Avoid using OATP1B1 and OATP1B3 substrates concurrently with Daybue if small changes in substrate plasma concentration could lead to serious toxicities.
Documentation Availability
Documents required to import Daybue (Trofinetide) to India?
Daybue (Trofinetide) solution can be imported by patients or treating physicians on behalf of patients. The following documentation is required to import the product:
- (i)2 ID proofs along with PAN card details along with attested scanned copies
- (ii)Valid doctor prescription scanned copy
- (iii)Doctor’s MCI number
- (iv)Doctor’s mobile number
- (v)Patients diagnostic reports
How is the order confirmed?
The order will be confirmed only after the receipt of:
- (i)The above-mentioned documents and drug availability.
- (ii)Import permit if applicable.
Sourcing & Delivery
The Rx4U team has extensive experience in sourcing Daybue (Trofinetide) from around the world, ensuring global access to the best available treatments for our customers. We are dedicated to promptly dispensing any valid prescription. All prescriptions are verified and dispatched directly to the patient’s address. Our patients are our top priority, and we strive to improve their lives through our services.
FAQ
Is Daybue FDA Approved?
Yes, Daybue was approved by the FDA in 2023.
What is the Mechanism of Action of Daybue?
Daybue (trofinetide) is a novel synthetic analogue of the amino-terminal tripeptide of IGF-1. It is designed to treat the core symptoms of Rett syndrome by potentially reducing neuroinflammation and enhancing synaptic function.
What is Daybue Used For?
Daybue is primarily used to treat Rett syndrome, a rare and severe neurological disorder that mainly affects girls and women. It helps alleviate some of the symptoms associated with this condition.
How is Daybue Administered?
Daybue is available as an oral solution and is typically taken twice daily, in the morning and evening.
What are the Common Side Effects of Daybue?
Common side effects of Daybue include diarrhea and vomiting. Weight loss is another potential side effect.
Is it Safe to Buy Daybue Online from India?
Yes, you can safely purchase Daybue online in India through https://rx4u.in/.
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