Medical Use
Aduhelm is an antibody targeting amyloid beta, used in treating Alzheimer’s disease (AD). It’s recommended to begin treatment in patients experiencing mild cognitive impairment or in the early stages of dementia.
Dosage Instructions: After an initial titration period, the advised dosage of Aduhelm is 10 mg/kg. This is administered via an intravenous (IV) infusion over about 60 minutes, every four weeks, with a minimum interval of 21 days between doses.
If a dose is missed, resume the infusion at the same dosage as soon as possible. Ensure that infusions are scheduled every four weeks, maintaining at least a 21-day gap between them.
Warning & Precautions
Aduhelm 170 mg therapy can lead to amyloid-related imaging abnormalities-edema (ARIA-E), visible on MRI as brain edema or sulcal effusions, and amyloid-related imaging abnormalities-hemosiderin deposition (ARIA-H), which includes microhemorrhages and superficial siderosis.
Pre-Treatment Requirements: Obtain a recent brain MRI (within the last 12 months) before starting treatment. The safety of Aduhelm in patients with pre-existing localized superficial siderosis, 10 or more brain microhemorrhages, or a brain hemorrhage larger than 1 cm within 12 months prior to therapy initiation has not been established.
Monitoring: Brain MRIs should be conducted before the 7th infusion (first dose of 10 mg/kg) and the 12th infusion (sixth dose of 10 mg/kg) of Aduhelm 300 mg to check for asymptomatic ARIA. Enhanced clinical vigilance is required for patients with radiographic findings of ARIA.
Adverse Reactions: Urticaria and angioedema were reported in one patient during the placebo-controlled period of Studies 1 and 2, emerging during the infusion. If any symptoms of a hypersensitivity reaction are observed, immediately discontinue the infusion and initiate appropriate therapy.
Documentation Availability
Documents required to import ADUHELM to India?
ADUHELM (aducanumab-avwa) injection can be imported by patients or treating physicians on behalf of patients. The following documentation is required to import the product:
- 2 ID proofs along with PAN card details along with attested scanned copies
- Valid doctor prescription scanned copy
- Doctor’s MCI number
- Doctor’s mobile number
- Patients diagnostic reports
How is the order confirmed?
The order will be confirmed only after the receipt of:
- The above-mentioned documents and drug availability.
- Import permit if applicable.
Sourcing & Delivery
The Rx4U team has extensive experience in sourcing ADUHELM (aducanumab-avwa) injection from around the world, ensuring global access to the best available treatments for our customers. We are dedicated to promptly dispensing any valid prescription. All prescriptions are verified and dispatched directly to the patient’s address. Our patients are our top priority, and we strive to improve their lives through our services.
FAQ
What is the generic name for Aduhelm®?
The generic name for Aduhelm® is aducanumab-avwa.
Who manufactures Aduhelm®?
Aduhelm® is manufactured by Biogen Inc.
Is Aduhelm® FDA approved?
Yes, Aduhelm® received FDA approval on June 7, 2021.
What is the dosage and form of Aduhelm®?
Aduhelm® is available as an injection in two forms: 170 mg/1.7 mL (100 mg/mL) and 300 mg/3 mL (100 mg/mL), provided in single-dose vials for intravenous administration.
What are the common side effects of Aduhelm®?
Common side effects include headache, ARIA-H superficial siderosis, superficial siderosis, ARIA-Edema, and ARIA-H microhemorrhage.
How much does Aduhelm® cost in India?
The cost of Aduhelm® in India can vary. For procurement, you can reach out to Rx4u team.
What are the storage conditions for Aduhelm®?
Store unopened vials in their original carton to protect from light. Keep them refrigerated at 2°C-8°C (36°F-46°F). Do not freeze or shake.
Is it safe to buy Aduhelm® online in India?
Yes, Aduhelm® can be purchased online in India through https://rx4u.in/
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